On hearing the names of “Tapentadol” (TapenTadol Cash on Delivery available) and “Tramadol”, the only thing that should be suggested here is that both these medicines are prescribed for pain relief with having different effects and side effects.
Hold on! Do you know that Tapentadol is a new version of Tramadol? Tapentadol overcomes some of the liabilities of Tramadol. Although these drugs are very similar, still we would like to throw light on their role individually.
Tramadol
Tramadol is a drug which is used for pain relief. But instead of giving much relief from pain, it is having a lot of side effects too.
Tramadol is known as one of the best choices for pain relief but as it is a prodrug, so it does not itself gets absorbed. It gets metabolized into the body by the cytochrome P450 enzymes into a few active chemicals.
There is the risk of serotonin syndrome and seizures with Tramadol due to the following reasons:
- As Tramadol require metabolic action to work, and in the case if there are patients having liver disease fail to clear metabolically and here the problem arises.
- Patients who are having little Metabolism to M1 need lots of efforts to achieve analgesia and this leads to SNRI metabolites in their body system.
So, it could be said that patients with different problems are having different experiences with this drug.
Tapentadol
Now it’s time to introduce Tapentadol. As it is already told that it is a new version of Tramadol, was first released in 2008. In comparison to Tramadol, it does not require metabolic action in order to show its effects.
Tapentadol leaves more effects on noradrenaline reuptake instead of leaving many effects on Serotonin reuptake.
Constipation, nausea, and vomiting with some dizziness in up to a third of patients are some of the side effects of the Tapentadol.
This drug is considered beneficial for pain relief, but still, there is no accurate data about the safety of this drug. So, it is required that there should be proper clinical outcomes so that we could say that it is the best drug to use.
Tapentadol advantages over Tramadol:
- The efficiency of cytochrome P450 drug communications
- Fewer chances of seizures
- Fewer chances of serotonin syndrome
- Earlier onset of action
- Fewer chances of nausea and vomiting
Tramadol advantages over Tapentadol:
- Fewer chances of respiratory depression, drowsiness, and lethargy
- Fewer chances of abuse potential
- There is wide availability of generic formulations
Wrapping up
The summary of the whole comparison makes us believe that Tapentadol is better than Tramadol. Although it is having side effects still are tolerable and the rest are not predicted yet. For any Query regarding TapenTadol Cash on delivery, call us at 3476762610 now and get assistance from our 24/7 customer support.
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